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In this National Vital Statistics Report, the authors present 2015 data on U.S. births according to a wide variety of characteristics, including maternal age, live-birth order, race and Hispanic origin, marital status, attendant at birth, method of delivery, period of gestation, birthweight, and plurality. Selected data by mother's state of residence and birth rates by age and race of father also are shown, and trends in fertility patterns and maternal and infant characteristics are described and interpreted. In 2015, 3,978,497 births were registered in the U.S., down less than 1 percent from 2014. The general fertility rate was 62.5 per 1,000 women aged 15–44, a decline of 1 percent from 2014. The birth rate for teenagers aged 15–19 fell 8 percent in 2015, rates for women in their 20s declined, but those for women in their 30s and early 40s increased. The total fertility rate declined to 1,843.5 births per 1,000 women in 2015. Modified Author Abstract.